Table 2.
Effect of aqueous anise suspension on ethanol-induced histopathological changes in rat stomach
| Group serial | Treatment and dose (mg/kg, body weight/day) |
Histopathological changes |
|||||||
| Congestion | Haemorrhage | Edema | Necrosis | Inflammatory changes | Dysplastic changes | Erosions | Ulceration | ||
| 1 | Control (distilled water) | - | - | - | - | - | - | - | - |
| (1 mL/rat) | |||||||||
| 2 | Ethanol, 80% (1 mL/rat) | ++ | +++ | ++ | ++ | + | + | +++ | + |
| 3 | Pimpinella anisum | + | + | + | - | - | - | + | - |
| (250) + ethanol, 80% (1 mL/rat) | |||||||||
| 4 | Pimpinella anisum | + | + | + | - | - | - | + | - |
| (500) + ethanol, 80% (1 mL/rat) | |||||||||
-: normal, +: moderate, ++: severe, +++: intensely severe.