Table 3.
Multivariate analyses of factors associated with cardiovascular disease among 1221 subjects (748 men and 473 women)
| Total (n = 1221) | Model 1 | Model 2 | Model 3 | |||
| Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | |
| NAFLD | 3.57 (1.47-8.67) | 0.005 | (-) | (-) | 4.12 (1.58-10.75) | 0.004 |
| The metabolic syndrome | (-) | (-) | 2.61 (1.03-6.60) | 0.042 | 1.38 (0.49-3.86) | 0.54 |
| Age, 10 yr | 1.61 (0.97-2.66) | 0.064 | 2.08 (1.30-3.33) | 0.002 | 2.12 (1.32-3.41) | 0.002 |
| The Brinkman index, 100 index1 | 1.06 (0.97-1.16) | 0.18 | 1.05 (0.96-1.14) | 0.28 | 1.03 (0.95-1.12) | 0.48 |
| Systolic blood pressure, 10 mmHg | 1.60 (1.26-2.04) | < 0.001 | (-) | (-) | (-) | (-) |
| LDL-C, mmol/L | 1.19 (0.70-2.03) | 0.52 | 1.35 (0.8-2.3) | 0.26 | 1.24 (0.73-2.08) | 0.43 |
| Men (n = 748) | Model 1 | Model 2 | Model 3 | |||
| Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | |
| NAFLD | 2.78 (0.98-7.89) | 0.054 | (-) | (-) | 3.56 (1.16-10.95) | 0.027 |
| The metabolic syndrome | (-) | (-) | 2.06 (0.70-6.11) | 0.19 | 1.13 (0.34-3.78) | 0.84 |
| Age, 10 yr | 1.59 (0.90-2.80) | 0.11 | 1.90 (1.11-3.23) | 0.019 | 1.96 (1.15-3.34) | 0.014 |
| The Brinkman index, 100 index1 | 1.07 (0.97-1.18) | 0.19 | 1.05 (0.95-1.15) | 0.35 | 1.04 (0.95-1.13) | 0.44 |
| Systolic blood pressure, 10 mmHg | 1.51 (1.10-2.07) | 0.011 | (-) | (-) | (-) | (-) |
| LDL-C, mmol/L | 1.42 (0.74-2.71) | 0.29 | 1.53 (0.81-2.90) | 0.19 | 1.42 (0.76-2.65) | 0.27 |
| Women (n = 473) | Model 1 | Model 2 | Model 3 | |||
| Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | |
| NAFLD | 14.33 (1.98-103.57) | 0.008 | (-) | (-) | 7.32 (1.22-43.84) | 0.029 |
| The metabolic syndrome | (-) | (-) | 4.59 (0.78-27.10) | 0.093 | 2.86 (0.42-19.39) | 0.28 |
| Age, 10 yr | 1.87 (0.60-5.78) | 0.28 | 3.28 (1.09-9.86) | 0.035 | 3.04 (0.99-9.31) | 0.051 |
| The Brinkman index, 100 index1 | 0.46 (0.03-6.76) | 0.57 | 0.55 (0.04-7.63) | 0.65 | 0.41 (0.03-6.44) | 0.53 |
| Systolic blood pressure, 10 mmHg | 1.88 (1.23-2.86) | 0.003 | (-) | (-) | (-) | (-) |
| LDL-C, mmol/L | 0.62 (0.21-1.85) | 0.39 | 0.87 (0.30-2.52) | 0.80 | 0.77 (0.27-2.16) | 0.62 |
NAFLD: nonalcoholic fatty liver disease; LDL-C: low dense lipoprotein cholesterol.
1
The Brinkman index is the number of cigarettes per day multiplied by years of smoking. A higher value indicates increased smoking-associated health hazard.