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. 2007 Apr 7;13(13):1947–1952. doi: 10.3748/wjg.v13.i13.1947

Table 1.

Cell cycle distribution of HCT-15 and HT-29 cells after treatment with various concentrations of 5-FU, celecoxib and 5-FU and celecoxib

HCT-15 SubG1 (%) G0/G1 (%) S (%) G2/M (%)
Control 2.75 51.94 14.61 30.90
5-FU 10-6 mol/L 2.49 37.35 18.93 41.40
10-5 mol/L 2.97 0.91 11.25 84.96
10-4 mol/L 2.77 0.26 27.09 70.13
10-3 mol/L 43.33 15.93 20.54 20.55
Celecoxib 10-7 mol/L 1.95 42.00 17.54 38.87
10-6 mol/L 4.14 58.80 15.85 21.60
10-5 mol/L 1.70 37.45 15.96 45.32
10-4 mol/L 31.99 7.45 33.10 27.67
5-FU (10-3 mol/L) & Celecoxib 10-7 mol/L 3.88 0.46 14.48 81.43
10-6 mol/L 4.18 0.56 32.86 62.73
10-5 mol/L 40.46 6.95 28.35 24.55
HT-29 SubG1 (%) G0/G1 (%) S (%) G2/M (%)
Control 2.12 60.49 4.62 32.84
5-FU 10-6 mol/L 8.92 73.77 3.73 13.85
10-5 mol/L 17.51 62.56 3.13 17.13
10-4 mol/L 37.70 47.87 3.63 10.87
10-3 mol/L 68.27 25.69 1.68 4.61
Celecoxib 10-7 mol/L 8.29 62.37 6.11 23.53
10-6 mol/L 9.66 60.02 7.24 23.29
10-5 mol/L 9.68 60.69 6.39 23.44
10-4 mol/L 26.10 54.30 4.02 15.76
5-FU (10-3 mol/L) & Celecoxib 10-7 mol/L 18.78 69.39 1.89 9.99
10-6 mol/L 36.15 46.46 3.16 14.35
10-5 mol/L 43.34 41.34 2.74 12.61