Table 4.
Complexity evolution in HCV quasispecies from SVR and NR patients in ISDR, PKRbd and V3 domains
Patient | Time of treatment domains | D0 ISDR-PKRbd-V3 | M3 ISDR-PKRbd-V3 | M6 ISDR-PKRbd-V3 |
SVR1 | n = 15 | 3–4–3 | - | - |
SVR2 | n = 13 | 3–4–2 | - | - |
SVR3 | n = 8 | 3–5–3 | - | - |
SVR4 | n = 16–13 | 3–7–3 | 3–4–3 | - |
SVR5 | n = 15–17 | 8–8–1 | 4–7–1 | - |
SVR6 | n = 17–6 | 8–9–3 | 1–2–3 | - |
SVR7 | n = 15–17 | 6–6–7 | 6–7–7 | - |
NR1 | n = 17–9–4 | 6–8–7 | 3–4–4 | 1–3–2 |
NR2 | n = 17–12–10 | 7–8–2 | 5–8–3 | 3–4–6 |
NR3 | n = 14–11–12 | 6–7–4 | 5–7–3 | 4–5–2 |
Amino acids sequences were compared to HCV-J; n: number of PCR products analyzed.