Table 5.
Placebo Controlled Trials in NAFLD
| Author (Year) | n | Method of Diagnosis |
Dose | Duration | Outcome1 |
|---|---|---|---|---|---|
| Zhu [34] | 144 | Ultrasound | 6,000 | 24 weeks | FOU, ALT, Lipids |
| Chen [35] | 46 | Ultrasound | 5,000 | 24 weeks | FOU |
| Cussons [36] 2 | 25 | Ultrasound | 4,000 | 8 weeks | FOU |
| Sofi [33] | 11 | Ultrasound | 830 | 12 months | FOU |
| Nohili [32] 3 | 60 | Ultrasound/ Liver Biopsy |
250/500 | 6 months | FOU |
| Dasarathy (present study) |
37 | NASH on Biopsy | 3,600 | 48 weeks | Liver Histology |
1
FOU = Fat on ultrasound
2
This was a crossover study
3
Only DHA used at two different doses: 250 and 500 mg