Fig. 7.

Synthesis of GATG glycodendrimers and schematic representation of the dynamic binding heterogeneity of surface-bound experiments between lectin clusters and glycodendrimers: a Initial binding of glycodendrimers to the lectin cluster with potential stabilization via chelate mechanism depending on glycodendrimer size and lectin cluster density. b At longer association times, competition between dendrimers for lectin complexation increases, promoting monovalent interactions primarily stabilized via rebinding effects. c An initial fast dissociation of glycodendrimers bound with low affinity is followed by d a slower dissociation due to stabilization by rebinding and potential chelate effects. Reprinted with permission from references (33) and (74)