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Covariate Analysis
| Covariate | Change in OFVa | p value |
|---|---|---|
| Time of administration (P-gp) | −155.6 | <0.05 |
| Time of administration (QCSF) | −37.7 | <0.05 |
| Time of administration (P-gp and QCSF) | −190.5 | <0.05 |
aChange in objective function value (OFV) after addition of the covariate on various parameters compared to the model that does not take into account time of administration on any of the parameters
