Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Simulated sensitivity of pharmacokinetic parameters to changing particle size after a single dose of 30 mg. Black line shows simulated exposures over a range of particle diameters assuming a monodisperse particle size distribution. Symbols show observed mean (±SD) exposures in study REL_BA1 for tablets containing coarsely and finely milled material with different polydisperse particle size distributions
