The V(D)J recombination machine is present in human epithelia-derived tumor cell lines. A-E: RT-PCR analysis of RAG1, RAG2, EBF, E2A, Pax5 in five cell lines. M: DL2000 Marker, 1. LoVo, 2. SW480, 3. HeLa, 4. SMC7721, 5. Bcap37; F: Immunoblot showing the expression of RAG1 and RAG2 in five cell lines.