. 2014 Apr 2;5(2):91–96. doi: 10.1016/j.shaw.2014.03.001

Table 4.

Median levels of biomarkers in exhaled breath condensate related to COPD severities^∗

	GOLD 0 (n = 53)	GOLD I (n = 27)	GOLD II (n = 10)	p^†
H₂O₂ (μM)	0.36 (44.2)	0.42 (47.3)	0.39 (47.7)	0.844
MDA (nM)	4.70 (39.2)	5.93 (52.6)	7.20 (59.9)	0.017
3-NT (nM)	3.31 (41.1)	6.81 (50.5)	7.77 (55.1)	0.146

3-NT, 3-nitrotyrosine; COPD, chronic obstructive pulmonary disease; FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; MDA, malondialdehyde.

^∗

COPD severity was categorized based on global initiative for chronic obstructive lung disease (GOLD) classification as follows: GOLD 0: FEV₁/FVC ratio ≥ 70% and FEV₁ ≥ 80% predicted. GOLD I (mild): FEV₁/FVC ratio < 70% and FEV₁ ≥ 80% predicted. GOLD II (moderate): FEV₁/FVC ratio < 70% and 50% ≤ FEV₁ < 80% predicted.

^†

Calculated by Kruskal–Wallis H test, median (mean rank).