Table 3.
Frequencies of Treg cell subsets determined by surface markers (CD4 and CD25) and intracellular FoxP3 levels (p < 0.01)
| Control | Acute | Chronic | |
|---|---|---|---|
| Expression of surface markers (%) | |||
| CD4+CD25+ cells | 6.7 ± 1.8 | 16.6 ± 4.2 | 27.6 ± 6.4 |
| CD4+CD25low cells | 4.7 ± 1.3 | 12.6 ± 3.4 | 21.2 ± 4.6 |
| CD4+CD25high cells | 2.0 ± 0.5 | 3.9 ± 1.1 | 6.8 ± 2.1 |
| Expression of intracellular Foxp3 molecule (%) | |||
| CD4+Foxp3+cells | 1.5 ± 0.6 | 5.7 ± 1.8 | 10.6 ± 2.5 |
| CD4+Foxp3low cells | 1.2 ± 0.5 | 4.0 ± 1.2 | 7.7 ± 1.5 |
| CD4+Foxp3high cells | 0.4 ± 0.2 | 1.6 ± 0.4 | 2.9 ± 0.60 |
| CD4+CD25+FoxP3+cells | 1.4 ± 0.48 | 5.06 ± 1.37 | 9.5 ± 2.06 |
| CD4+CD25lowFoxP3+cells | 1.11 ± 0.5 | 3.76 ± 0.94 | 7.09 ± 1.25 |
| CD4+CD25highFoxP3+cells | 0.41 ± 0.18 | 1.28 ± 0.47 | 2.45 ± 0.57 |
| CD4+CD25+FoxP3lowcells | 1.18 ± 0.48 | 3.57 ± 1.11 | 5.28 ± 1.32 |
| CD4+CD25+FoxP3highcells | 0.4 ± 0.2 | 1.41 ± 0.38 | 2.03 ± 0.4 |
Data are presented as mean ± SD.