Table 2.

Risk factors for death in adult patients hospitalized in intensive care unit (ICU) with incident candidemia due to a single isolate (logistic regression), YEASTS program, Paris area, October 2002 to September 2010

	Death before day 30			Death before day 8			Death between day 8 and day 30
	Adj. OR	95 % CI	p	Adj. OR	95 % CI	p	Adj. OR	95 % CI	p
Male gender							0.71	0.51–0.99	0.043
Age categories
<45 years	1		0.0001				1		0.0003
45–64 years	1.66	1.09–2.53					2.32	1.38–3.89
65–79 years	2.49	1.60–3.56					3.19	1.88–5.43
≥80 years	3.09	1.73–5.49					2.91	1.45–5.83
Arterial catheter	1.39	1.01–1.92	0.0430				1.47	1.02–2.11	0.0371
Surgery within 30 days	0.62	0.46–0.84	0.0017				0.54	0.39–0.76	0.0004
Species
C. albicans	1		0.0013	1		0.0031
C. grabrata	0.65	0.43–0.98		0.58	0.34–1.02
C. parapsilosis	0.43	0.25–0.76		0.18	0.06–0.52
C. tropicalis	0.99	0.61–1.63		1.00	0.53–1.86
C. krusei	1.78	0.71–4.47		1.55	0.57–4.23
C. kefyr	3.88	1.14–13.26		2.79	0.84–9.21
Preexposure to caspofungin	3.83	1.29–11.35	0.0153	3.54	1.09–11.53	0.0357
First-line treatment
Fluconazole	1		0.0003	1		<0.0001
Echinocandin	1.23	0.85–1.80		0.98	0.59–1.61
Other treatment	1.11	0.69–1.79		0.81	0.42–1.56
No treatment	4.34	2.23–8.45		11.04	5.72–21.30

Variables included in full model (with p < 0.25 in univariate analysis of death): male gender, age, arterial catheter, surgery within 30 days, malignancy, transplantation, preexposure to caspofungin, species, first-line treatment

Adj. OR adjusted odds ratio for hospital and year, 95 % CI odds ratio 95 % confidence interval, HSCT hematopoietic stem cell transplant, BMT bone marrow transplantation