. 2014 Aug 6;40(9):1303–1312. doi: 10.1007/s00134-014-3408-3

Table 3.

Risk factors for fungemia in intensive care unit (N = 1,206) due to C. glabrata, C. parapsilosis, C. tropicalis, C. krusei, C. kefyr, or multiple species in reference to fungemia due to C. albicans

	C. glabrata			C. parapsilosis			C. tropicalis
	Adj. OR^a	95 % IC^b	p	Adj. OR^a	95 % IC^b	p	Adj. OR^a	95 % IC^b	p
Male gender	1.07	0.78–1.48	0.660	1.10	0.71–1.69	0.683	1.27	0.81–1.99	0.294
Age less than 45 years	1			1			1
Between 45–64 years	1.60	0.96–2.67	0.074	0.77	0.45–1.32	0.340	1.09	0.59–2.02	0.788
Between 65–79 years	2.02	1.19–3.43	0.009	0.55	0.30–1.01	0.055	1.54	0.81–2.90	0.187
80 years and more	2.68	1.43–5.01	0.002	0.73	0.33–1.60	0.428	0.95	0.38–2.38	0.916
Central venous catheter	1.00	0.69–1.45	0.988	1.36	0.79–2.32	0.263	1.25	0.73–2.14	0.413
Arterial catheter	0.90	0.64–1.27	0.545	0.96	0.60–1.53	0.856	0.91	0.56–1.49	0.710
Surgery within 30 days	1.09	0.79–1.52	0.596	1.27	0.82–1.98	0.291	1.01	0.64–1.61	0.957
No malignancy	1			1			1
Hematological malignancy	1.08	0.63–1.86	0.771	0.57	0.25–2.29	0.179	2.22	1.24–3.99	0.007
Solid tumor	1.09	0.74–1.60	0.658	0.59	0.32–1.10	0.096	0.49	0.25–0.97	0.042
Solid organ transplantation	0.74	0.42–1.31	0.305	0.76	0.38–1.51	0.428	0.75	0.35–1.62	0.469
HIV infection	0.51	0.19–1.39	0.188	1.08	0.39–3.03	0.879	0.92	0.34–2.45	0.861
Intravenous drug addiction	2.01	0.34–11.90	0.444	NC			NC
Caspofungin pre-exposure	16.63	3.51–78.76	<0.001	17.86	3.27–97.46	0.001	3.42	0.29–39.68	0.326
Fluconazole pre-exposure	4.09	2.26–7.41	<0.001	1.02	0.33–3.09	0.976	3.48	1.63–7.46	0.001

	C. krusei			C. kefyr			“Mixed” infections
	Adj. OR^a	95 % IC^b	p	Adj. OR^a	95 % IC^b	p	Adj. OR^a	95 % IC^b	p
Male gender	1.65	0.74–3.71	0.222	0.74	0.29–1.88	0.532	1.06	0.52–2.19	0.865
Age less than 45 years	1			1			1
Between 45–64 years	0.73	0.28–1.90	0.513	1.90	0.39–9.38	0.429	1.27	0.39–4.07	0.691
Between 65–79 years	0.88	0.30–2.60	0.811	2.97	0.59–14.86	0.184	1.46	0.43–5.00	0.543
80 years and more	1.43	0.33–6.23	0.632	1.02	0.09–11.91	0.990	4.19	1.15–15.31	0.030
Central venous catheter	0.92	0.39–2.16	0.849	0.80	0.27–2.33	0.677	1.47	0.58–3.70	0.412
Arterial catheter	0.51	0.21–1.24	0.136	1.45	0.52–4.01	0.480	0.92	0.44–1.95	0.832
Surgery within 30 days	0.40	0.17–0.92	0.032	0.58	0.21–1.59	0.291	1.28	0.60–2.71	0.528
No malignancy	1			1			1
Hematological malignancy	2.07	0.72–5.93	0.177	2.06	0.57–7.40	0.270	1.23	0.33–4.58	0.757
Solid tumor	3.11	1.29–7.49	0.012	1.42	0.47–4.29	0.536	1.68	0.74–3.83	0.215
Solid organ transplantation	3.06	1.13–8.31	0.028	0.54	0.07–4.45	0.569	1.45	0.45–4.64	0.530
HIV infection	1.72	0.42–7.04	0.452	NC			1.19	0.21–6.84	0.848
Intravenous drug addiction	NC			NC			13.71	1.77–106.28	0.012
Caspofungin pre-exposure	51.86	8.44–318.52	<0.001	16.93	1.29–221.63	0.031	12.51	1.05–149.70	0.046
Fluconazole pre-exposure	6.43	2.32–17.83	<0.001	4.33	0.88–21.24	0.071	0.77	0.10–6.02	0.800

Multivariate multinomial regression analysis, YEASTS program, Paris area, October 2002 to September 2010

Adj. OR adjusted odds ratio for year, 95 % CI odds ratio 95 % confidence interval