Table 1. Results of BRAF Genotyping by Histological Subtype.
Histological subtype | Total | BRAFV600E | |
---|---|---|---|
N=69 | No. | % | |
Tumors derived from Langerhans cells | 48 | 23 | 48 |
Langerhans cell histiocytosis | 42 | 22 | 52 |
Solitary/unifocal | 25 | 12 | 48 |
Multi-system | 13 | 7 | 54 |
Disseminated/visceral | 4 | 3 | 75 |
Langerhans cell sarcoma | 6 | 1 | 17 |
Tested Non-Langerhans cell entities | 21 | 0 | 0 |
Dendritic cell sarcoma | 3 | 0 | 0 |
Juvenile Xanthogranuloma | 3 | 0 | 0 |
Rosai-Dorfman Disease | 4 | 0 | 0 |
Granular Cell Tumor | 11 | 0 | 0 |
Abbreviations: N, number of cases, No., number of mutated cases.