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. 2014 May 13;5(12):4195–4210. doi: 10.18632/oncotarget.1966

Figure 2. Inhibition of endogenous PCs activity in colon cancer cells by Spn4A.

Figure 2

(A-B), Using specific primers, the expression of indicated PCs was assessed by Real time-PCR on RNA extracted from HT-29 (A) and CT-26 (B) cells. (C–F), Endogenous PCs activity was assessed by ability of indicated cells to process proPDGF-A and proIGF-1R using an anti-V5 (C and D) and anti–IGF-1R antibody (E and F), respectively. Bars denote the corresponding percentages of pro-PDGF-A and pro-IGF-1R processing. Values are mean ± SD (n = 3 per group). *P < 0.05; **P < 0.001. *** P < 0.0001.