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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Bioorg Med Chem. 2014 Apr 16;22(11):2919–2938. doi: 10.1016/j.bmc.2014.04.014

Figure 5.

Figure 5

Initial exploration of pyrazole core via Vilsmeier-Haack reaction by the introduction of the first diversity element (R1).