Table 1.

Research agenda on the cost-effectiveness and implementation of integration of non-communicable disease (NCD) management with HIV care for people in low- and middle-income countries (LMICs).

1) To assess the cost-effectiveness of NCD management for PLHIV in LMICs, collect data on: Epidemiology: to determine prevalence, incidence, and attributable mortality by demographics and region Quality of Life: to examine the impact of co-morbid NCD diagnoses and their treatments Screening: to evaluate the test characteristics, yield, and outcomes Treatment: to assess the availability and outcomes of NCD management strategies Costs: to quantify the resource use of screening, treatment, and management of NCD clinical outcomes

2) To investigate optimal strategies for integration of expanded screening and treatment of NCDs in PLHIV, collect data on: Outcomes: to measure clinical and economic outcomes with both distinct as well as integrated care Time points: to determine short-term and long-term outcomes, including linkage to and retention in care

3) To utilize existing clinical and research platforms, extend research training in LMICs in the following fields: Clinical epidemiology Implementation science Cost-effectiveness analysis Mathematical modeling