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. 2014 Aug 4;6(8):2310–2335. doi: 10.3390/toxins6082310

Figure 1.

Figure 1

Repression of txpA expression by stimulation of mRNA degradation. The txpA toxin mRNA (blue) can be translated by the ribosome (purple) to produce the toxic protein. However, if the antitoxin RatA (red) is present and interacts with the toxin, RNase III can cleave the double-stranded complex, thereby initiating mRNA degradation which eventually prevents toxin translation.