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. 2014 Aug 13;6(8):2424–2431. doi: 10.3390/toxins6082424

Figure 1.

Figure 1

Quantity and quality of memory B cells are similar early and late post-vaccination in individuals with similar humoral responses. Humoral responses of AVA-vaccinated individuals collected early (3–6 months) or late (2–5 years) after their last vaccination did not differ by protective antigen (PA) ELISA (A, p = 0.21) and in vitro lethal toxin (LT) neutralization (B, p = 0.43). Similarly, PA-specific ASCs (C) and anti-PA IgG per ASC in culture supernatants (D) were not significantly different (p = 0.52, p = 0.41, respectively) between early and late post-vaccination individuals. Groups were compared by two-tailed Mann-Whitney U. Each symbol indicates a single individual, bars indicate median values.