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3D reconstructions of sub-core and core assemblies. 3D structural studies revealed BTV core is organized in two concentric protein layers with the sub-core composed of VP3 (A) forming a scaffold for VP7 to give rise to cores (B). (C) Cross-sectional representation of core assemblies shows intra-core organization of minor proteins VP1 (RdRp polymerase), VP4 (capping enzyme) and VP6 (helicase) in association with dsRNA in relation to VP3 and VP7 [57].
