Table 1.

Performance on 454 (top) and IonTorrent (bottom) datasets

		Original	Allpaths-LG		Coral		Coral*		Fiona		HybridShrec*		HybridShrecF
Dataset		e-rate	e-rate	gain	e-rate	gain	e-rate	gain	e-rate	gain	e-rate	gain	e-rate	gain
D.melanogaster	18×	1.17	1.07	8.87	0.72	38.81	0.55	53.30	0.42	64.62	4.46	−279.51	0.73	38.17
E.coli K-12	13×	1.06	0.74	30.68	0.54	49.42	0.38	63.79	0.25	76.88	0.64	40.05	0.70	34.28
S.aureus	34×	1.76	1.34	23.85	1.76	0.00	0.44	74.90	0.53	69.87	1.59	9.62	1.40	20.50
S.cerevisae	16×	0.95	0.78	18.45	0.95	0.56	0.92	2.99	0.61	36.04	0.90	5.48	0.73	23.11
B.pertussis	85×	3.71	2.22	40.13	3.71	0.02	2.57	30.60	1.01	72.83	12.44	−235.48	4.07	−9.68
E.coli K-12	8×	0.62	0.28	54.46	0.33	46.86	0.30	51.86	0.06	90.52	0.36	41.81	0.37	40.26
E.coli K-12	163×	1.46	1.23	15.99	0.59	59.70	0.38	73.72	0.27	81.24	1.73	−18.90	1.46	0.00
E.coli K-12	156×	1.11	0.75	31.98	0.43	61.07	0.28	74.70	0.29	74.06	1.38	−24.15	1.11	0.00
E.coli O104:H4	32×	5.19	3.09	40.53	5.19	0.00	3.44	33.82	1.59	69.33	4.39	15.36	4.31	16.76
H.sapiensa	11×	1.62	1.44	11.52	—b		—b		0.87	46.68	—b		—b
P.falciparum 3D7	13×	5.06	3.97	21.39	5.05	0.03	3.80	24.94	2.33	54.12	7.67	−51.29	4.63	8.50
S.aureus	109×	3.32	2.83	14.89	3.32	0.24	1.44	56.91	1.17	64.94	3.77	−13.44	3.31	0.32

Note: ^aThe programs were run on machine with 16 physical and 32 virtual cores and 370 GB of RAM. ^bOut of memory—The table shows the base error rate (e-rate, in percent) before and after correction with the methods as well as the gain statistic. For each dataset, the results with the best gain value are highlighted in bold. The results are separated by sequencing technology, the 454 results are above the IonTorrent results.