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. 2014 Aug 22;30(17):i422–i429. doi: 10.1093/bioinformatics/btu449

Table 1.

Modification of existing pathway analysis methods for iPAS

graphic file with name btu449t1.jpg

Note. Significance can be obtained against the null distribution generated from normal samples. All the collected normal samples for the nRef are one by one compared with the nRef to yield statistics of the null distribution. A statistic from a single cancer case is compared with this null distribution to yield P-value.