Table 2.
Survival analysis of ‘cell cycle stimulatory’ pathway reported by Bryant et al. (2010)
| Dataset | Pathway statistics | Coefficient | P-value |
|---|---|---|---|
| Beer (N = 432), Bryant et al., Overall survival | Average Za | 0.37 | 0.00011 |
| Beer (N = 442) Overall survival | Average Zb | 0.62 | 0.00003 |
| Fisher | 0.50 | 0.00068 | |
| GSEA | 0.65 | 0.00001 | |
| Euclidean | 0.65 | 0.00001 | |
| Mahalanobis | 0.67 | 0.00001 | |
| GSE8894 (N = 61) Recurrent free survival | Average Zb | 0.90 | 0.01163 |
| Fisher | 0.91 | 0.01076 | |
| GSEA | 0.78 | 0.02899 | |
| Euclidean | 0.87 | 0.01544 | |
| Mahalanobis | 0.68 | 0.05485 | |
aDerived from mean and SD of all cancer samples in the dataset, bDerived by mean and SD of the nRef.