Fig. 3.

Comparison of TEMPI with two previous methods. (A) Precision, recall and F1 score for TEMPI-${\mathit{G}}^{\mathit{t}}$, PNA-${\mathit{G}}^{\mathit{t}}$ and Simple-${\mathit{G}}^{\mathit{t}}$ with up to 90% removal of the input PPIs. The performance can vary depending on which PPIs are removed. Thus, we performed 10 times of random samplings. Data are represented as mean ± SD from the samplings. (B–C) Distributions of correlations of temporal profiles of degrees (B) and CC (C) in the three ${\mathit{G}}^{\mathit{t}}$ s with those in the true ${\mathit{G}}^{\mathit{t}}$. (D) Changes in the interactivities of GOBPs 60, 67 and 218 in the three ${\mathit{G}}^{\mathit{t}}$ s and the true ${\mathit{G}}^{\mathit{t}}$ (Left) and correlations between the interactivities in the inferred ${\mathit{G}}^{\mathit{t}}$ s and the true ${\mathit{G}}^{\mathit{t}}$ (Right). See the legend for the lines used for the three methods