. Author manuscript; available in PMC: 2014 Aug 28.

Published in final edited form as: J Strength Cond Res. 2012 Jul;26(7):1740–1748. doi: 10.1519/JSC.0b013e31825c2bef

Table 5.

Mean (± SEM) CSA, MVC, and 1RM pre- and pre- to post-RT of trained arm by ANKRD6 genotype.^*

Phenotype	ANKRD6 122 Q>E
	QQ (N = 658)	QE (N = 27)	EE^† (N = 0)
Pre-RT CSA (cm²)	16.4 ± 0.1^‡	18.2 ± 1.0^‡
Absolute CSA Δ (cm²)	3.1 ± 0.1	3.3 ± 0.4
Relative CSA Δ (%)	19.4 ± 0.4	18.6 ± 2.0
	ANKRD6 631 P>L
	PP (N = 510)	PL (N = 166)	LL (N = 10)
Pre-RT CSA (cm²)	16.5 ± 0.2	16.2 ± 0.3	15.1 ± 1.6
Absolute CSA Δ (cm²)	3.2 ± 0.1^§	2.9 ± 0.1^§	2.5 ± 0.4
Relative CSA Δ (%)	19.7 ± 0.4	18.4 ± 0.7	16.1 ± 1.7
	ANKRD6 710 L>X
	LL (N = 721)	LX (N = 18)	XX (N = 2)
Pre-RT MVC (kg)	45.4 ± 0.5	37.0 ± 1.6	32.5 ± n/a
Absolute MVC Δ (kg)	8.1 ± 0.3^‖	3.9 ± 1.0^‖	9.6 ± n/a
Relative MVC Δ (%)	21.5 ± 0.9^¶	11.3 ± 4.1^¶	29.5 ± n/a
	ANKRD6 545 T>A
	TT (N = 454)	TA (N = 10)	AA^† (N = 0)
Pre-RT 1RM (kg)	9.2 ± 0.1	9.5 ± 0.4
Absolute 1RM Δ (kg)	4.1 ± 0.1^#	4.8 ± 0.6^#
Relative 1RM Δ (%)	52.1 ± 1.5	57.6 ± 7.8

CSA = cross-sectional area; MVC = maximum voluntary contraction; IRM = 1 repetition maximum; RT = resistance training; ANKRD6 = Ankyrin Repeat Domain 6. Muscle phenotype values displayed have been adjusted for age, body mass index, and gender. Genotype main effects by genotype: ANKRD6 122 Q>E (p = 0.014), ANKRD6 631 P>L (p = 0.018), ANKRD6 710 L>X (p = 0.035), ANKRD6 545 T>A (p = 0.032).

^†

The common allele frequency approached 1 for the common allele and 0 for the heterozygous minor allele (10).

^‡

QQ vs. QE, p = 0.076.

^§

PP vs. PL, p = 0.062.

^‖

LL vs. LX, p = 0.074.

^¶

LL vs. LX, p = 0.075.

TT vs. TA, p = 0.069; Δ = change.