Table 2.
Treatment Group | Glomerulosclerosis Index | Podocyte Hypertrophy | Tubular Casts/Cysts |
---|---|---|---|
Tg26;PODRDH9+vehicle | 0 | 0 | 0.59±0.13 |
Tg26;PODRDH9+doxycycline | 32±19.64a | 2.47±0.84a | 7.81±6.43a |
Kidney histologic analysis was performed in Tg26;PODRDH9 mice treated with doxycycline or vehicle. The glomerulosclerosis index, podocyte hypertrophy, and tubular casts/cysts were quantified as described in the Concise Methods.
P<0.05 compared with the vehicle group.