Table 1.
Clinical Characteristics | Microarray Discovery | PCR Validation | |||||||
---|---|---|---|---|---|---|---|---|---|
| |||||||||
AR (n=60) | STA (n=62) | p value | Training Set | Test Set | |||||
| |||||||||
AR (n=23) | STA (n=24) | p value | AR (n=32) | Non-AR (n=166) | p value | ||||
Recipients | |||||||||
Gender, % females | 31.91% | 44.64% | 0.19 | 20.00% | 47.37% | 0.09 | 52.00% | 36.49% | 0.41 |
Mean age, year | 12.49±5.04 | 10.94±6.01 | 0.17 | 10.31±5.24 | 14.24±5.87 | 0.05 | 11.91±5.57 | 11.85±5.69 | 0.78 |
Immunosuppression, %SF | 51.06% | 57.14% | 0.54 | 66.67% | 73.68% | 0.67 | 44% | 44.6% | 1.00 |
HLA match | 2.45±1.36 | 2.41±1.41 | 0.90 | 3.13±1.41 | 2.59±1.43 | 0.27 | 1.22±1.19 | 1.39±1.23 | 0.09 |
| |||||||||
Donors | |||||||||
Donor Source %LRD | 63.64% | 75.51% | 0.21 | 80.00% | 84.21% | 0.76 | 24.00% | 41.89% | 0.36 |
Gender, % females | 53.49% | 48.00% | 0.60 | 46.67% | 63.16% | 0.35 | 40.00% | 41.89% | 1.00 |
Mean age, year | 33.26±13.10 | 32.72±11.03 | 0.83 | 32.41±13.87 | 39.17±10.31 | 0.13 | 27.79±9.69 | 28.50±10.08 | 0.59 |
Values are means ± SD (Standard Deviation) AR, Acute rejection; STA, stable; SF, steroid free; txp, transplant; LRD, living related donor. The sample numbers for each dataset are shown. Discovery, and Training Set samples came from 137 unique Stanford patients; Test Set samples came from 99 unique SNSO1 patients. The Verification set samples came from a subset of samples used for Microarray Discovery.