Table 2.
Genotype Frequencies in the Study Population for At-Risk Control Subjects and Subjects with Acute Respiratory Distress Syndrome
Genotype Frequencies |
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---|---|---|---|---|---|---|---|---|---|---|---|
Minor Allele Frequency |
Controls | Cases | |||||||||
SNP | Allele | Location | Position* | All | Controls | Cases | P Value† | Genotype | (%) | (%) | HWE P Value‡ |
rs2664581 | A > C | Exon 2 | 43,237,936 | 0.178 | 0.168 | 0.212 | 0.0336 | AA | 430 (69.81) | 139 (62.05) | 0.298 |
AC | 165 (26.79) | 77 (34.38) | |||||||||
CC | 21 (3.41) | 8 (3.57) |
Definition of abbreviations: HWE, Hardy-Weinberg equilibrium; SNP, single-nucleotide polymorphism.
Chromosome position based on National Center for Biotechnology Information Build 36.3.
The probability of the Chi-square test for comparison of allele frequencies.
Chi-square test for deviation from HWE in the control group.