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. 2014 Aug;51(2):169–177. doi: 10.1165/rcmb.2013-0298OC

Figure 3.

Figure 3.

Altered NgBR level affects in vitro angiogenesis in PAECs. (A) Baseline in vitro tube formation was impaired in IPH PAECs; NgBR overexpression rescued the in vitro tube formation defects of IPH PAECs. (B) NgBR overexpression increased the migration of IPH PAECs, as demonstrated by the decreased gap for IPH PAECs overexpressing NgBR. (C) NgBR knockdown with siRNA-2 impaired in vitro tube formation of control PAECs. (D) NgBR knockdown decreased the migration of control PAECs, as demonstrated by increased gap for control PAECs treated with NgBR siRNA-2. (E) NgBR knockdown did not affect cell viability and growth. Open bar, control; closed bar, NgBR knockdown. *P < 0.05 compared with empty plasmid; †P < 0.05 compared with NS siRNA. Data are shown as mean (± SE).