Table 1.
Pulmonary Inflation Pressure and Cardiovascular Parameters Are Not Changed by Obesity, Diet, or Treatment with Streptozotocin or Insulin
| Treatment Group | Ppi (mm H2O) | Heart Rate (beats/min) | Systolic BP (mm Hg) | Diastolic BP (mm Hg) | Animal Number |
|---|---|---|---|---|---|
| OP/HFD | 108 ± 9 | 328 ± 24 | 85 ± 3 | 53 ± 3 | 11 |
| OR/HFD | 110 ± 6 | 363 ± 22 | 70 ± 6 | 47 ± 7 | 12 |
| OP/LFD | 101 ± 5 | 337 ± 28 | 74 ± 11 | 46 ± 7 | 11 |
| OR/LFD | 106 ± 3 | 355 ± 17 | 73 ± 5 | 51 ± 6 | 9 |
| OP/HFD/STZ | 108 ± 2 | 418 ± 20 | 75 ± 7 | 46 ± 1 | 5 |
| OR/HFD/STZ | 118 ± 7 | 313 ± 20 | 89 ± 3 | 49 ± 5 | 6 |
| OP/LFD/STZ | 108 ± 8 | 318 ± 23 | 77 ± 5 | 50 ± 6 | 6 |
| OR/LFD/STZ | 124 ± 10 | 344 ± 44 | 71 ± 8 | 41 ± 5 | 5 |
| OP/HFD/STZ/INS | 104 ± 4 | 452 ± 22 | 88 ± 17 | 62 ± 6 | 6 |
| OR/HFD/STZ/INS | 108 ± 7 | 410 ± 34 | 77 ± 6 | 51 ± 5 | 6 |
Definition of abbreviations: BP, blood pressure; HFD, high-fat diet; INS, insulin; LFD, low-fat diet; OP, obese prone; OR, obese resistant; Ppi, pulmonary inflation pressure; STZ, streptozotocin.