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. Author manuscript; available in PMC: 2014 Aug 28.
Published in final edited form as: Endocrine. 2010 Nov 19;39(3):235–241. doi: 10.1007/s12020-010-9429-y

Fig. 4.

Fig. 4

Insulin therapy down-regulated SREBP-1 in the liver of diabetic rats. a Expression of SREBP-1. b Expression of nSREBP-1. β-actin and SP3 protein were used as controls for protein loading. The relative signal levels were determined by densitometry. Each bar represents mean ± SD (n = 4–6). *P < 0.05 vs. NC; #P < 0.05 vs. DM. NC normal control rats; DM diabetic rats with no therapy; INS diabetic rats treated with insulin