Table III.
Genes differentially regulated T-Rapa6 cells relative to T-Rapa12 cells.
| Gene Ontology Family Up | Gene Symbol (Reference) |
T-Rapa6 vs. T- Rapa12 |
|
|---|---|---|---|
| Up-Regulated Families | |||
| Response to Hypoxia | FLT1 ([39]) | 14-fold up | |
| Regulation of Apoptosis | IER3 ([40]) | 7-fold up | |
| Regulation of Cell Motion | PDGFA ([41]) | 4-fold up | |
| Sterol Hormone Synthesis | ADM ([42]) | 5-fold up | |
| Immune System Regulation | CD86 ([43]) | 18-fold up | |
| Down-Regulated Families | |||
| Antigen Processing and Presentation | HLA-DRA([44]) | 4-fold down | |
| Protein Ubiquitination | CDKN2A ([45]) | 3-fold down | |
| Cell Death | XAF1 ([46]) | 9-fold down | |
| Macromolecule Metabolic Process | KLF2 ([47]) | 78-fold down | |
| JAK-STAT Cascade | JAK2 ([48]) | 4-fold down | |