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. 2014 May 27;5(13):4779–4787. doi: 10.18632/oncotarget.2029

Figure 1. JMJD2C is cleaved by caspase-3-like protease.

Figure 1

(A) Expression of JMJD2C protein in 8 breast-tumor samples was analyzed by western blotting with anti-JMJD2C (A300-885A) antibody. (B) Schematic representation of the structure of JMJD2C. (C) Schematic representation of A300-885A antibody mapping. Cell lysates of HeLa and MDA-MB-231 were analyzed by western blotting with A300-885A antibody. Where indicated, cells were treated with 20 mM z-DEVD-fmk, for 2 h before treatment. HeLa and MDA-MB-231 cells were treated with TNF-α (25 ng/ml) or CHX (10 μg/ml) for 6 h or with the combination for 6 h.