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. 2014 Jun 7;5(13):4990–5001. doi: 10.18632/oncotarget.2071

Figure 1. Ibrutinib and AZD2014 synergistically induce apoptosis.

Figure 1

(A) Cells were cultured with the indicated concentrations of compounds for 72 hours. The number of viable cells was measured by Alamar Blue. Numbers represent percent growth inhibition. 100 = no growth; 200 = total cell death. (B) and (C) Cells were treated with Ibrutinib (10nM) and/or AZD2014 (200nM). (B) Cells were stained with trypan blue and counted at the indicated time points. Error bars indicate standard deviation (n=3). (C) Cells were collected for Western blot analysis at 24 hours.