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. 2014 Jul 25;8(8):7723–7732. doi: 10.1021/nn5002694

Figure 2.

Figure 2

(A) Negative stain TEM of AH vaults showing significant internalized mass within a majority of the NPs (white arrowheads). (B) Negative stain TEM of AH vaults following treatment with 5% Tween 20 indicating a loss in the internalized mass prominence and frequency, suggesting a dynamic, detergent-soluble nature. (C) CryoET tilt image showing the internalized additional mass associated with AH vaults can traverse the entire vault lumen (complete, white arrowheads; incomplete, white arrows).