doxorubicin (580 g/mol) |
50 |
1.27 (PubChem) |
0.5 h at 4 °C, 20 h centrifugation |
10 μg:1000 μg (129:1) |
none detected |
UV/vis spectra, DOXε480nn = 11 500 M–1 cm–1
|
amphotericin B (924 g/mol) |
0.75 |
0.8 (DrugBank) |
0.5 h at 4 °C, 20 h centrifugation |
10 μg:1000 μg (80:1) |
5.6 ng:l μg (45:1) |
UV/vis spectra, AMBε406 nm = 150 000 M–1 cm–1
|
0.5 h at 4 °C, 5 min spin column |
10 μg:100 μg (815:1) |
149.2 ng:l μg (1213:1) |
UV/vis spectra, AMBε406 nm = 150 000 M–1 cm–1
|
0.5 h at 4 °C, 5 min spin column |
50 μg:100 μg (4075:1) |
254.7 ng:l μg (2071:1) |
UV/vis spectra, AMBε406 nm = 150 000 M–1 cm–1
|
all-trans retinoic acid (300 g/mol) |
insoluble |
6.30 (DrugBank) |
0.5 h at 4 °C, 20 h centrifugation |
10 μg:1000 μg (250:1) |
7.3 ng:l μg (182:1) |
UV/vis spectra, ATRAε350 nm = 44,300 M–1 cm–1
|
bryostatin 1 (905 g/mol) |
insoluble |
4.25–5.40 (predicted, ChEMBL and ChemSpyder) |
0.5 h at 4 °C, 1 h centrifugation |
1 μg:100 μg (83:1) |
13.4 ng:l μg (83:1) |
mass spec (MRM-LC-MS/MS) |