Table 2.

Apparent affinity values of P2Y₁₂R antagonists determined in cells expressing the recombinant human P2Y₁₂R using a cAMP assay and a cAMP-dependent reporter gene assay.

Antagonist	cAMP assay	Reporter gene assay
	pKB/pA2*	pKB/pA2*
PSB-0739	10.1	9.8*
Cangrelor	9.2#	8.6
Reactive blue 2	6.7	7.4*
Suramin	5.7*	5.5
MRS2395	Attenuation of responses at 20 μM

The * indicates a pA₂ value; values determined in the reporter gene assay and values marked with ^# are taken from Hoffmann et al, 2009.