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. 2014 Aug 28;10(8):e1004533. doi: 10.1371/journal.pgen.1004533

Figure 6. The filamin domain of LIN-41 is not essential for the germline function.

Figure 6

A. Left: fluorescent micrographs of gonads of the indicated genotypes immunostained for LIN-41. Right: corresponding maximum intensity projections of DAPI staining of the proximal-most region of the gonads shown on the left. Scale bars: 25 µm. B. Amino acid sequences of the filamin domain for wild-type and lin-41(ma104) mutant (derived from a cDNA sequence). C. Crystal structure of the LIN-41 filamin domain. The domain is presented as a cartoon model in rainbow colors from blue (N-terminus) to red (C-terminus) with a transparent surface. The position and sequence of the 16-residue insert present in the lin-41(ma104) allele in the second β-strand is highlighted. The disordered sequence stretch 730–757 which is not included in the model is displayed as grey dots.