Table 5. Characteristics of patients that had DENV RNA/IgM antibody detected in CSF.
Patient | Age (y) | Gender (M/F) | Illness day | Rash | HCT | PLT | SGOT | SGPT | Vomiting | Headache | Convulsion | Fever | Neck stiffness | Cranial nerve palsies | GCS | Outcome$ | WCC | Neu (%) | Lymph (%) | Lactate (mmol/l) | CSF/blood glucose | Protein (g/l) | DENV diag. | Other Path detected |
1 | 30 | F | 26 | N | 44 | 160000 | NA | NA | Y | Y | N | N | N | Y | 15 | 5 | 120 | 12 | 88 | 4.4 | 0.49 | 2.1 | IgM CSF | EBV CSF PCR |
2 | 32 | M | 3 | N | 41 | 388000 | 60 | 62 | N | Y | N | N | Y | N | 15 | 5 | 200 | 18 | 82 | 2.4 | 0.65 | 0.54 | IgM CSF | N |
3 | 25 | M | 8 | N | 49 | NA | 52 | 142 | N | Y | NA | N | Y | N | 15 | 5 | 310 | 64 | 36 | 2.4 | 0.77 | 1.06 | IgM CSF | N |
4 | 39 | M | 30 | N | 41 | 232000 | 56 | 60 | Y | Y | N | N | NA | N | 15 | 5 | 86 | 7 | 93 | 1.5 | 0.48 | 0.45 | IgM CSF | N |
5 | 25 | M | 22 | N | 43 | NA | NA | NA | N | Y | N | N | N | N | 15 | 5 | 173 | 1 | 99 | 3.4 | 0.42 | 0.9 | IgM CSF | EBV CSF PCR |
6 | 31 | M | 3 | N | 42 | NA | NA | NA | Y | Y | N | Y | N | NA | 15 | 2 | 354 | 4 | 96 | 1.5 | 0.64 | 1 | IgM CSF | N |
7 | 38 | M | 6 | N | 44 | 197000 | NA | NA | N | Y | Y | Y | Y | N | 12 | 5 | 600 | 75 | 25 | 1.8 | 0.63 | 0.94 | IgM CSF | N |
8 | 15 | F | 5 | N | 49 | 387000 | NA | NA | Y | Y | N | N | Y | N | 13 | 5 | 160 | 8 | 92 | 2.9 | 0.76 | 0.26 | IgM CSF | N |
9 | 17 | F | 3 | N | 34 | 147000 | 28 | 35 | N | Y | Y | Y | N | N | 7 | 4 | 252 | 8 | 92 | 2.2 | 0.55 | 1.51 | IgM CSF | N |
10 | 21 | M | 3 | N | 45 | 186000 | 41 | 29 | Y | Y | Y | Y | Y | N | 10 | 5 | 288 | 7 | 93 | 2.4 | 0.60 | 1.45 | IgM CSF | HSV CSF PCR |
11 | 42 | F | 4 | N | 39 | 182000 | 62 | 71 | N | Y | N | N | N | N | 8 | 2 | 4 | 70 | 30 | 4 | 0.72 | 0.6 | RNA CSF | N |
12 | 36 | M | 9 | N | 43 | 131000 | 27 | 104 | Y | Y | NA | Y | NA | N | 7 | 1 | 36 | 0 | 100 | 2.4 | 0.58 | 0.7 | IgM CSF | HSV CSF PCR |
13 | 15 | M | 2 | Y* | 36 | 120000 | 41 | 25 | NA | NA | NA | Y | Y | N | 7 | 5 | 188 | 4 | 96 | 1.6 | 0.55 | 0.8 | IgM CSF | RUBELLA IgM |
14 | 15 | F | 9 | Y# | 36 | 167000 | 42 | 22 | Y | Y | Y | Y | N | N | 9 | 5 | 49 | 15 | 43 | 2.3 | 0.63 | 0.5 | IgM CSF | N |
15 | 67 | F | 2 | N | 39 | 300000 | 32 | 40 | Y | Y | NA | Y | N | N | 15 | 3 | 4 | NA | NA | 2.4 | 0.48 | 0.4 | RNA CSF | N |
16 | 28 | M | 14 | N | 38 | 389000 | 49 | 91 | Y | Y | N | Y | Y | N | 14 | 2 | 20 | 25 | 75 | 0.9 | 0.58 | 0.2 | IgM CSF | N |
17 | 38 | M | 6 | N | 37 | 384000 | 24 | 104 | N | Y | N | N | NA | N | 15 | 5 | 20 | 10 | 90 | 1.3 | 0.64 | 0.75 | IgM CSF | N |
18 | 16 | F | 3 | N | 34 | 369000 | NA | NA | N | Y | N | N | N | N | 15 | 5 | 365 | 4 | 89 | 2 | 0.48 | 1.43 | IgM CSF | N |
19 | 22 | M | 5 | N | 43 | 130000 | 263 | 193 | N | N | Y | N | Y | N | 14 | 5 | 58 | 4 | 76 | 1.3 | 0.70 | 0.94 | IgM CSF | N |
Note: y: years; M: male, F: female; HCT: haematocrit; PLT: platelet; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic-pyruvic transaminase; GCS: Glasgow coma score; WCC: white blood cell; Neu: neutrophils; Lymph: lymphocyte; NA: not available, Y: yes; N: No;
*non-confluent maculopapular rash suggestive of rubella infection,
details not recorded;
1: Death; 2: Severe sequelae; 3: Moderate sequelae; 4: Mild sequelae; 5: Full recovery; patients with high platelet count (>150000 per microliter) are in bold.