FIGURE 5:
Bmi1 Activates PIK/AKT and stabilization of Snail. (A) Western blot analysis of Akt, GSK-3β, Snail, phosphorylated-Akt, and phosphorylated-GSK-3β in Hk2 cells under normoxia. (B) Western blot analysis of Akt, GSK-3β, Snail, E-cadherin, vimentin, p-Akt, and p-GSK-3β expression in Ly294002- or wortmannin-treated HK-2 cells under normoxia. Representative blot from three independent experiments.