Table 1. Characteristics of studies eligible for meta-analysis.
Author, Year, Region | Number(male%) | Age(years) | IntervalBetweenBiopsyand FIB-4 | Liver BiopsyScoringsystem | LiverBiopsyLength | Blinded |
Chen[10], 2013, China | 148 (66%) | 40.36±11.2 | ≤7d | Metavir | >15 mm | Yes |
Kim[13], 2010, Korea | 668 (66%) | 39.1±14.8 | ≤2d | Batts and Ludwig | >15 mm | Yes |
Zhu[29], 2012, China | 159 (71%) | 42 (18∼62) | unclear | METAVIR | ≥15 mm | unclear |
Ucar[18], 2013, Turkey | 73 (64%) | 42.81±12.86 | unclear | METAVIR | unclear | Yes |
Gong[21], 2013, China | 41 (73%) | 50.8±10.3 | unclear | METAVIR | unclear | unclear |
Wang[20], 2013, China | 231 (68%) | 34.1±9.8 | <1d | Scheuer | >15 mm | Yes |
Ji[17], 2011, China | 313 (69%) | 35.6±11.2 | 1d | METAVIR | 20 mm | unclear |
Başar[25], 2013, Turkey | 76 (55%) | unclear | <1d | METAVIR | >10 mm | Yes |
Bonnard[19], 2010, France | 59 (68%) | 35±9 | 0.5–10 m | METAVIR | 21±6 mm | Yes |
Erdogan[11], 2013, Turkey | 221 (63%) | 43.68±12.56 | ≤1d | Ishak | unclear | Yes |
Wu[30], 2010, China | 78 (85%) | 32.6±12.3 | unclear | METAVIR | >15 mm | unclear |
Mallet[16], 2009, France | 138 (71%) | 42±15 | <1d | METAVIR | 17.6±6.8 | unclear |
Seto[24], 2011, China | 237 (68%) | 38.2 (18∼63) | same time | Ishak | ≥15 mm | Yes |
Zhu[27], 2011, China | 175 (78%) | 36.5±9.4 | ≤7d | METAVIR | >15 mm | Yes |
Liu[23], 2012, China | 114 (80%) | 38.32±11.36 | same time | METAVIR | 15∼20 mm | unclear |
Wang[26], 2013, China | 149 (93%) | 37 (30∼42) | ≤2d | Scheuer | >10 mm | Yes |
Xun[28], 2013, China | 197 (76%) | 31 (21–45) | same time | Scheuer | >15 mm | unclear |
Zhang[32], 2009, China | 86 (60%) | 39 (16–64) | <1d | METAVIR | 15∼20 mm | unclear |
Zhang[22], 2012, China | 361 (62%) | 36±11 | ≤7d | Scheuer | unclear | unclear |
Zhang[31], 2010, China | 212 (88%) | 31±7 | 1day | Scheuer | 20 mm | Yes |