Table I.

Ontological analysis of the genes modulated by WWOX overexpression: cellular pathways.

Cellular pathway	No. of genes
Unclassified	2,041
Inflammation mediated by chemokine and cytokine signaling pathway	39
Wnt signaling pathway	38
Heterotrimeric G-protein signaling pathway (Gi α and Gs α mediated)	32
Integrin signalling pathway	28
Interleukin signaling pathway	25
Angiogenesis	22
PDGF signaling pathway	21
Huntington disease	21
Alzheimer disease-presenilin pathway	20
p53 pathway	20
Parkinson disease	20
Heterotrimeric G-protein signaling pathway (Gq α and Go α mediated)	20
PI3 kinase pathway	19
TGF-β signaling pathway	18
EGF receptor signaling pathway	17
Endothelin signaling pathway	15
Transcription regulation by bZIP transcription factor	14
Ionotropic glutamate receptor pathway	14
FGF signaling pathway	14
Cytoskeletal regulation by Rho GTPase	14
Apoptosis signaling pathway	13
Alzheimer disease-amyloid secretase pathway	13
Oxidative stress response	13
Nicotinic acetylcholine receptor signaling pathway	13
Metabotropic glutamate receptor group III pathway	13
Cadherin signaling pathway	13
Angiotensin II-stimulated signaling through G-proteins and β-arrestin	12
Ras pathway	11
p38 MAPK pathway	11
T cell activation	10
Insulin/IGF pathway-protein kinase B signaling cascade	10