Table II.
Ontological analysis of the genes modulated by WWOX overexpression: biological processes.
| Biological process | No. of genes |
|---|---|
| Metabolic process | 1,063 |
| Primary metabolic process | 1,019 |
| Cellular process | 777 |
| Unclassified | 629 |
| Cell communication | 556 |
| Signal transduction | 524 |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 472 |
| Protein metabolic process | 415 |
| Transport | 370 |
| Transcription | 295 |
| Transcription from RNA polymerase II promoter | 293 |
| Developmental process | 288 |
| Cell surface receptor linked signal transduction | 256 |
| Immune system process | 243 |
| Regulation of transcription from RNA polymerase II promoter | 240 |
| System process | 220 |
| Protein transport | 192 |
| Intracellular protein transport | 192 |
| Neurological system process | 176 |
| Protein modification | 174 |
| System development | 174 |
| Cell cycle | 163 |
| Response to stimulus | 156 |
| Intracellular signaling cascade | 148 |
| Proteolysis | 136 |
| Cell adhesion | 131 |
| Cell-cell signaling | 123 |
| Cellular component organization | 122 |
| Ectoderm development | 120 |
| Lipid metabolic process | 118 |
| Vesicle-mediated transport | 117 |
| G-protein coupled receptor protein signaling pathway | 114 |
| Nervous system development | 109 |
| Mesoderm development | 108 |
| Apoptosis | 101 |