Table 1. Unique non-synonymous mutations identified in circulating WHV derived from the liver virus-negative phase but not from the liver virus-positive phase of POI from 6/M and 7/M woodchucks.

	PreS	Polymerase	X	PreC
	766 bp (nt 2949-407)	1441 bp (nt 2949-407 & 1080–1755)	425 bp (nt 1503–1928)	212 bp (nt 1910–2122)
3/M	n.d.	n.d.	n.d.	V25F
4/M	A91N, T93N, P181L	S279K, N281L	n.d.	n.d.

For each of the WHV genome fragments sequenced, its length (bp) and location (nt) were enumerated according to the WHV/tm3 sequence (GenBank accession number AY334075). The amino acid change and location of each of the non-synonymous mutations identified were based on the predicated amino acid sequence of WHV/tm3. Only variants detected in 2 or more of 10 clones are reported.

Abbreviation: n.d. not detected.