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. 2014 Aug 28;10(8):e1004332. doi: 10.1371/journal.ppat.1004332

Table 3. Virus-host and virus-virus DNA junctions detected in livers and lymphoid tissues and cells of woodchucks with lifelong primary occult WHV infection.

Subgroup/Animal no. Tissue type Time of sample acquisition (m.p.i.) detected no. Overall virus-host DNA junction detected no. Characteristics of virus-host DNA junction Overall virus-virus junction
WHV sequence* Host sequence length (bp) Host sequence identity
With HCC
5/M Liver autopsy 55 2 S374-380 36 n.d. 2
S301-306 236 n.d.
Bone marrow 55 2 S575-569 272 n.d. 6
X1590-1583 170 n.d.
Liver biopsy 32 PS132-138 263 n.d. 2
Liver biopsy 20 2 X1877-1916 69 n.d. 0
P1338-1441 59 n.d.
9/M Liver autopsy 55 3 X1782-1808 246 n.d. 6
X1782-1810 264 H19; mouse 80%
P1149-1156 276 n.d.
Bone marrow 55 1 X1513-1627 83 n.d. 0
Liver biopsy 46 2 X1674-1386 82 n.d. 0
X1632-1317 35 n.d.
Liver biopsy 32 1 X1898-2060 66 n.d. 0
Without HCC
1/F Bone marrow 66 1 P1382-C2335 241 n.d. 4
PBMC 66 1 X1854-1861 198 n.d. 2
2/F Lymph node 34 4 C2039-2044 211 n.d. 6
P1479-1491 146 n.d.
S351-343 86 n.d.
PS56-61 78 n.d.
8/M Liver autopsy 22 1 X1636-P1343 219 n.d. 0
Bone marrow 22 2 X1636-1501 177 n.d. 0
X1853-1915 123 n.d. 0
10/M Liver autopsy 72 1 X1627-P1151 39 n.d. 0
Bone marrow 72 2 X1636-P1088 88 n.d. 0
X1616-1672 130 n.d. 0

* WHV X, S, P gene or preS (PS) genomic region sequence flanking virus-host junction.

Abbreviations: m.p.i., months post-infection; no., number; n.d., not determined; n.a., not applicable.