Figure 2.

Statistical interaction effect between α-tocopherol and γ-tocopherol on amyloid load based on an age-adjusted linear regression model with log₁₀ (α-tocopherol) and log₁₀ (γ-tocopherol) modeled as continuous variables in pmol/mg protein and their multiplicative term (p-value for interaction=0.03). The lines reflect the association between amyloid load and alpha tocopherol at three different values of gamma tocopherol: log₁₀ =1.7 at the 33^rd percentile (grey), log₁₀ =1.8 at the 50^th percentile (dotted), and log₁₀ =1.9 at the 67^th percentile (black). Higher levels of α-tocopherol were associated with increased amyloid load except when the levels of γ-tocopherol were also high, at which point higher levels of α-tocopherol were associated with lower amyloid levels.