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. 2014 Aug 27;14:228. doi: 10.1186/s12866-014-0228-0

Table 1.

Lethal dose 50% of H. pylori strains in Galleria mellonella

LD 50 (means ± SEM) *
Strains 48 h 72 h
G27 2.8 (±0.4) × 105 2.4 (±0.2) × 105
G27ΔcagA 3.1 (±0.04) × 106
G27ΔcagE 2.4 (±0.06) × 106
G27ΔcagPAI 2.0 (±0.01) × 106
60190 6.1 (±0.4) × 105 1.4 (±0.04) × 106
60190ΔvacA 8.2 (±0.04) × 106
60190ΔcagA 9.7 (±0.04) × 106
60190ΔcagE 9.5 (±0.06) × 106
60190Urease-negative 8.7 (±0.04) × 106
M5 12.8 (±0.3) × 105 2.1 (±0.08) × 105
M5 ggt::aph 12.0 (±0.6) × 105 1.0 (±0.1) × 105

*The LD50 values were expressed in Colony Forming Units (CFUs).