Table 1.
Baseline characteristics of CHOP and RCHOP patients before and after age, treatment intensity and propensity score matching
Before matching | After matching | ||||||||
---|---|---|---|---|---|---|---|---|---|
Characteristics | CHOP | RCHOP | Std. diff | P value | CHOP | RCHOP | Std. diff | P value | |
N = 1,196 | N =2,825 | N = 1,099 | N = 1,099 | ||||||
Age at diagnosis | |||||||||
Mean ± SD | 56 · 7 ± 16 | 65 · 5 ± 14 | 0 · 62 | <·001 | 57 · 5 ± 16 | 58 · 6 ± 15 | 0 · 07 | 0 · 12 | |
Age group | |||||||||
0-19 | 1% | <1% | 0 · 09 | <·001 | <1% | <1% | 0 · 00 | 1 · 00 | |
20-59 | 56% | 25% | 0 · 67 | 53% | 53% | 0 · 00 | |||
60-69 | 19% | 30% | 0 · 25 | 20% | 20% | 0 · 00 | |||
70-79 | 20% | 33% | 0 · 30 | 21% | 21% | 0 · 00 | |||
80+ | 5% | 12% | 0 · 22 | 6% | 6% | 0 · 00 | |||
Female | 47% | 48% | 0 · 01 | 0 · 74 | 47% | 48% | 0 · 00 | 0 · 93 | |
ACG group | |||||||||
0 | <1% | <1% | 0 · 09 | <·001 | <1% | <1% | 0 · 00 | 0 · 96 | |
1-3 | 7% | 5% | 0 · 10 | 7% | 7% | 0 · 02 | |||
4-6 | 24% | 17% | 0 · 18 | 23% | 23% | 0 · 00 | |||
7-9 | 28% | 31% | 0 · 05 | 29% | 31% | 0 · 03 | |||
10 + | 40% | 47% | 0 · 16 | 41% | 40% | 0 · 02 | |||
Income quintile | |||||||||
1 | 16% | 17% | 0 · 02 | 0 · 18 | 16% | 15% | 0 · 04 | 0 · 62 | |
2 | 20% | 21% | 0 · 02 | 19% | 20% | 0 · 02 | |||
3 | 20% | 19% | 0 · 02 | 21% | 21% | 0 | |||
4 | 24% | 21% | 0 · 08 | 23% | 24% | 0 | |||
5 | 20% | 22% | 0 · 06 | 20% | 20% | 0 · 01 | |||
Missing | <1% | <1% | 0 · 02 | <1% | <1% | 0 · 07 | |||
Severity of disease | |||||||||
Low | 32% | 30% | 0 · 04 | 0 · 04 | 31% | 31% | 0 · 00 | >0 · 99 | |
High | 54% | 58% | 0 · 08 | 56% | 56% | 0 · 00 | |||
Unclassifiable | 15% | 12% | 0 · 07 | 13% | 13% | 0 · 00 | |||
Histology code | |||||||||
9590 | 16% | 20% | 0 · 11 | <·001 | 16% | 16% | 0 · 01 | 0 · 92 | |
9591 | 3% | 3% | 0 · 02 | 3% | 2% | 0 · 03 | |||
9640 | 80% | 69% | 0 · 25 | 79% | 80% | 0 · 02 | |||
9680 | 2% | 9% | 0 · 29 | 2% | 2% | 0 · 00 | |||
Median Follow-up time (years) | 9 · 7 | 3 · 7 | 9 · 7 | 3 · 5 |
Std Diff, standardized difference; ACG, adjusted clinical group; Severity of disease was estimated using treatment intensity; Histology codes based on International Classification of Disease diagnosis codes.