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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: J Immunol. 2013 Feb 25;190(7):3068–3078. doi: 10.4049/jimmunol.1202441

FIGURE 1. Scheme of the construction of rPreS fusion proteins for vaccination against birch pollen allergy.

FIGURE 1

(A) Amino acid sequence of Bet v 1a. Peptide PA (light gray box) and peptide PB (dark gray box), which are part of the recombinant fusion proteins, as well as Bet v 1–derived peptides P1′– P6′ used for epitope-mapping experiments, are indicated. (B) Illustration of the four rPreS fusion proteins (2PA-PreS, 2PB-PreS, 4PA-PreS, 2PAPB-PreS). Peptide A (PA: light gray), peptide B (PB: dark gray), the carrier protein PreS (white), and the C-terminal hexahistidine tags (6xHis: black) are indicated.

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