FIGURE 5. Lymphocyte proliferation and cytokine responses of PBMCs from patients allergic to birch pollen.
PBMCs from six patients allergic to birch pollen were stimulated with equimolar amounts of rBet v 1, PA, PB, PreS fusion proteins, or PreS. Box plots of SI (A) and cytokines (B, C), for which 50% of the values are within the boxes; extremes and outliers are indicated by asterisks and circles, respectively. Horizontal lines represent median values. The mean cpm of unstimulated cells for the patients analyzed were A1: 1027.2; A20: 4674.3; A21: 2779.0; A25: 2066.8; A26: 9165.5; and A27: 748.0. *p < 0.05.